Accutane

[GuyOh]

my cousin took it and she had extreme dry lips and skin

[Freakazoid]

Originally Posted by ideliver

and to the fools that say the lawsuits are there for a reason...you are correct...they are there to make plaintiffs attorneys very wealthy...these are safe and reasonable medications...for informed adults under appropriate medical supervision...

I knew informed, intelligent, 'normal' adults who took accutane, exactly as directed. And they still had serious problems.

Accutane is NOT safe and reasonable in any fashion... It's not worth that risk with the alternatives out there.

[hl0m4n]

i took accutane at 18 and it was the miracle for acne . i was so fucking happy and amazed at the results.

i got blood test every week. i paid $3 per box under insurance but damn i remember the retail on the box of pills was $350 for those without insurance.

anyway, i took accutane for 1.5 years so i was 19 when i stoped. it did wonders on my face and the only side effect i had was dry skin which i solved by using avon non oily lotion with spf. nothing was of concern. some people said here extremely dry skin or whatnot but i guess each person responds to it differently and mine was very positive.

the lotion was great, really didn't get the skin oily & no smell.

PS: iirc, you can't donate blood while your on accutane and for 1-2 years after you finished or something.

[TiAg335i]

Originally Posted by hl0m4n

i took accutane at 18 and it was the miracle for acne . i was so fucking happy and amazed at the results.

i got blood test every week. i paid $3 per box under insurance but damn i remember the retail on the box of pills was $350 for those without insurance.

anyway, i took accutane for 1.5 years so i was 19 when i stoped. it did wonders on my face and the only side effect i had was dry skin which i solved by using avon non oily lotion with spf. nothing was of concern. some people said here extremely dry skin or whatnot but i guess each person responds to it differently and mine was very positive.

the lotion was great, really didn't get the skin oily & no smell.

PS: iirc, you can't donate blood while your on accutane and for 1-2 years after you finished or something.

yeh, probably because accutane is a teratogen and can deform developing fetuses

[ideliver]

Originally Posted by Freakazoid

I knew informed, intelligent, 'normal' adults who took accutane, exactly as directed. And they still had serious problems.

Accutane is NOT safe and reasonable in any fashion... It's not worth that risk with the alternatives out there.

So you know better than the FDA and tens of thousands of satisified patients....most patients that receive accutane describe it as life changing...

So you would know like to live in a world of PERFECTION and without risk...better trade that BMW in for a government approved car, with a government approved loan

Oh wait...this was a government approved medication....

So just like all of those fools in Cali that did not vaccinate their children to pertussis....because they knew better than the medical establishment and evil drug companies...they are now burrying their children

It's simple...if you don't like Accutane...don't use it, just don't deny others the same option

[sb335is]

haah i heard a good one
my buddy told me once he was getting a bj from some chick on it, a few minutes in she looks up and says

"your dick is dry"
so he says
"just fucking spit on it"

[JayKay335i]

Originally Posted by Freakazoid

I knew informed, intelligent, 'normal' adults who took accutane, exactly as directed. And they still had serious problems.

Accutane is NOT safe and reasonable in any fashion... It's not worth that risk with the alternatives out there.

Its called pharmakogenetics. Look it up.

[Freakazoid]

Originally Posted by JayKay335i

Its called pharmakogenetics. Look it up.

I gotta ask...how is it you know the term, but you don't know how to spell it? (not a rip...just generally curious).

Nonetheless I agree and can see where you're coming from this with certain medications, however, I personally believe accutane is a slightly different beast, refer to next post.

[Freakazoid]

Originally Posted by ideliver

So you know better than the FDA and tens of thousands of satisified patients....most patients that receive accutane describe it as life changing...

So you would know like to live in a world of PERFECTION and without risk...better trade that BMW in for a government approved car, with a government approved loan

Oh wait...this was a government approved medication....

So just like all of those fools in Cali that did not vaccinate their children to pertussis....because they knew better than the medical establishment and evil drug companies...they are now burrying their children

It's simple...if you don't like Accutane...don't use it, just don't deny others the same option

Are you talking out of your ass, or have you stopped following this POS of drug?

Most patients that take accutane describe it as life-changing? You can say that about ANY drug among the years, that means absolutely nothing if there is a high possibility of having long-term, life altering NEGATIVE changes.

You know they *recalled* the drug right? (yes i know the bullshit thing that it was for 'business reasons'. right.... nothing to do with the tens of millions of dollars in lawsuits they had to pay out on....).

You can have your opinion, and state it. And I can have mine. I'm simply stating what I've seen first hand, like others here have been doing. I'm not 'denying' him from it (wtf?). I'm WARNING him, just like the *black box warning* (for those that don't know this is basically the strongest 'warning' the FDA has) that is is/was required on Accutane..


I'm not stating it doesn't work, I'm not saying it's a bullshit drug, I'm saying that it's not worth the risks, from my personal exposure (through multiple people, not direct). do you really want IBD, Crohn's, etc etc? (ignoring mental effects, etc). anyways that's my 2 cents.

[Freakazoid]

Originally Posted by TiAg335i

yeh, probably because accutane is a teratogen and can deform developing fetuses

a good point, but lots of effective, *good* drugs are like that.

[achenator]

my wife took Accutane in her late 20's. She had brain swelling and had to get off of it immediately. A total pain in the ass as she had to wait and be on BC pills for a couple months before she could even start taking the Accutane. She only was on the Accutane a couple of weeks before she started having horrible headaches.

[JayKay335i]

Originally Posted by Freakazoid

I gotta ask...how is it you know the term, but you don't know how to spell it? (not a rip...just generally curious).

Nonetheless I agree and can see where you're coming from this with certain medications, however, I personally believe accutane is a slightly different beast, refer to next post.

My pharm. professors German. Half the stuff he writes is some odd collaboration of the two languages.

That just happens to be in German.

[wj4]

Originally Posted by JayKay335i

My pharm. professors German. Half the stuff he writes is some odd collaboration of the two languages.

That just happens to be in German.

That's how it is, man. Scientists are smart, but bad writers. I read a lot of articles from scientific journals, primary for my adv toxicology course, and most are horribly written. (Given that they're translated to English from a foreign language).

PS...how bad does your acne has to be for a prescription for the Accutane? The derm I visited said that it is absolutely the very last resort. I assume you can't just walk in and ask for the Accutane w/o having try several topical stuff first?

[ideliver]

Originally Posted by hl0m4n

PS: iirc, you can't donate blood while your on accutane and for 1-2 years after you finished or something.

it is for one month...not 1-2 years...

[ideliver]

Originally Posted by wj4

That's how it is, man. Scientists are smart, but bad writers. I read a lot of articles from scientific journals, primary for my adv toxicology course, and most are horribly written. (Given that they're translated to English from a foreign language).

PS...how bad does your acne has to be for a prescription for the Accutane? The derm I visited said that it is absolutely the very last resort. I assume you can't just walk in and ask for the Accutane w/o having try several topical stuff first?

Correct...the indication is "severe recalcitrant nodular acne"

The problem with Accutane is not the drug...the problem is that it is over-used

Too many lazy patients who just want the "easy fix"...they do not want to hassle with topicals (that work well...like EpiDuo)...so they doctor shop until they get what they want...

this is who Accutane is for...

[JayKay335i]

Originally Posted by wj4

That's how it is, man. Scientists are smart, but bad writers. I read a lot of articles from scientific journals, primary for my adv toxicology course, and most are horribly written. (Given that they're translated to English from a foreign language).

PS...how bad does your acne has to be for a prescription for the Accutane? The derm I visited said that it is absolutely the very last resort. I assume you can't just walk in and ask for the Accutane w/o having try several topical stuff first?

Its a last resort. No respectable doctor would put you on it without trying some orals and topicals first.

[ideliver]

Originally Posted by Freakazoid

a good point, but lots of effective, *good* drugs are like that.

correct...off the top of my head...alcohol, ace inhibitors, ARBs, vitamin A, valproic acid, dilantin, lithium, SSRI (paxil prozac zoloft), doxycycline, tetracycline, bactrim (all sulfa drugs), all of the floroquinolones (cipro), uncontrolled diabetes, all statins (lipitor), all chemotherapy drugs (obviously)

[wj4]

Originally Posted by ideliver

Correct...the indication is "severe recalcitrant nodular acne"

The problem with Accutane is not the drug...the problem is that it is over-used

Too many lazy patients who just want the "easy fix"...they do not want to hassle with topicals (that work well...like EpiDuo)...so they doctor shop until they get what they want...

this is who Accutane is for...Attachment 432770

ideliver-just curious, do you work in the field? Seems you are more knowledgeable than the average Joe.

In the case of the gentleman from above, do you know if his case is spread out to the face and chest as well, or is it just the back area? And the final picture, are those scars? Or still in the process of being healed?

[JayKay335i]

In that final picture, those are going to scar. All the granulation tissue forming during the cyst formation is what tends to lead to the nasty scarring associated with acne.

[wj4]

Originally Posted by JayKay335i

In that final picture, those are going to scar. All the granulation tissue forming during the cyst formation is what tends to lead to the nasty scarring associated with acne.

Hmm interesting.

Freakazoid- the pharmaceutical industry is a multi billion dollar industry, man. With that said, ethnic and moral are put aside. If the drug is profitable to the general public, a few guinea pigs getting the short end of the stick won't hurt anyone. Sad to say, but this is how it is.

[hl0m4n]

^ damn man, that pic is not normal acne, shit is like very abnormally severe...

either way to OP, like others have mentioned accutane is a last resort the derma will recommend. if you been through the topicals and still have acne and your derma opens the option, the choice is ultimately up to you.

although there is alot of good info posted on here, we are all different and your body will react to it differently. if you decide to go on it, by all means. just follow the dosage, do the blood tests, and go to the derma checkups. follow what your derma says and there should be no problem.

having used it, it has worked greatly for me with absolutely no downside. shit was really a miracle, i was amazed after a week of taking it the difference it made. after using it though, my acne never came back to what it was.

& jaykay bro, you back in AZ? how many years you got left before res? not too long before you making the 6 fig .

[JayKay335i]

How you doing dude!? Still rocking the 335 or did you ever get that c63? I should be back in NY in 2-3 years depending on externship rotation locations.

I personally dont think that the pharmaceutical industry is that bad. Yes, its about money, but its also about science and helping people. Drugs cost A LOTTTTT of money to develop. They cost a lot of money to produce and it costs a lot to handle the legal department.

When it comes to drugs you have to weight the side effects to the benefit of taking them. Chemo drugs, they'll F you up, but the other result is death. Thats an extreme example but there are many similar situations that wont cause death but have serious side effects. Also, many useful drugs have extremely narrow therapeutic ranges before causing toxicity not to mention the ridiculous list of interactions they can have.

They're great and horrible all rolled up in one. As Paracelcus put it, "the dose makes the poison".